About this test
PTCB Practice Test 1 is a 20-question mini exam that mirrors the real PTCE in miniature: the same four knowledge domains in the same proportions as the official 2026 content outline (Medications 35%, Patient Safety 23.75%, Order Entry 22.5%, Federal Requirements 18.75%). It is built for a focused study session or a quick daily rep when you don't have two hours for the full 90-question exam.
Each numbered test in this series draws from its own dedicated set of questions, so Test 1 and Test 2 never overlap. Every answer comes with a source-cited explanation, turning a wrong answer into a mini lesson.
New to the material? Work through our 2026 PTCB study guide first, then reinforce it with the full PTCB practice test and PTCB Practice Test 2.
What's in the question bank
| Topic | Questions in bank |
|---|---|
| Brand Generic | 2 |
| Drug Class | 2 |
| Lasa | 2 |
| High Alert | 2 |
| Sig Codes | 2 |
| Side Effects | 1 |
| Indication | 1 |
| Ndc | 1 |
Sample questions with answers
These 8 questions come straight from the 32-question bank the timed test above draws from. Work each one before you open the answer: recalling it cold is what moves it into long-term memory.
1. A man is prescribed Flomax (tamsulosin) to improve urine flow. Tamsulosin is most commonly used to treat which condition?
- A.A urinary tract infection
- B.Overactive bladder
- C.Erectile dysfunction
- D.Benign prostatic hyperplasia (BPH)
Show answer and explanation
Correct answer: D. Benign prostatic hyperplasia (BPH)
Tamsulosin is an alpha blocker that relaxes smooth muscle in the prostate and bladder neck to relieve the urinary symptoms of benign prostatic hyperplasia (BPH). It does not treat infection or erectile dysfunction, so those distractors describe unrelated therapies.
2. A patient cannot swallow omeprazole delayed-release capsules. Which alternative administration method is acceptable?
- A.Crush the whole capsule and stir it into hot tea
- B.Open the capsule, sprinkle the intact granules on a spoonful of applesauce, and swallow the mixture immediately without chewing
- C.Chew the capsule thoroughly before swallowing
- D.Dissolve the capsule in milk overnight and drink it at breakfast
Show answer and explanation
Correct answer: B. Open the capsule, sprinkle the intact granules on a spoonful of applesauce, and swallow the mixture immediately without chewing
The capsule may be opened and its granules mixed with a tablespoon of soft, cool applesauce, then swallowed immediately with water; the granules must not be chewed or crushed, and the mixture must not be stored. Crushing destroys the delayed-release coating that protects the drug from stomach acid, which is why the tea and chewing options are wrong.
3. Under the Controlled Substances Act, a drug with a high potential for abuse and no currently accepted medical use in the United States is placed in which schedule?
- A.Schedule I
- B.Schedule II
- C.Schedule III
- D.Schedule V
Show answer and explanation
Correct answer: A. Schedule I
Schedule I substances, such as heroin and LSD, are defined by a high potential for abuse and no currently accepted medical use in the United States, so they may not be prescribed or dispensed. Schedules II through V all contain drugs with some accepted medical use, with abuse potential decreasing as the schedule number increases.
4. While a technician enters a new prescription, the pharmacy system displays a serious drug-drug interaction alert. What must the technician do?
- A.Pass the alert to the pharmacist for clinical review rather than bypassing it
- B.Override the alert if the patient has filled both drugs before
- C.Cancel the prescription and contact the prescriber directly
- D.Lower the entered dose until the alert no longer appears
Show answer and explanation
Correct answer: A. Pass the alert to the pharmacist for clinical review rather than bypassing it
Drug utilization review findings and drug interactions are pharmacist-intervention issues under PTCE area 3.3. Resolving an interaction alert requires clinical judgment about risks, alternatives, and monitoring, which is outside the technician's role. Overriding alerts without review is a well-documented path to patient harm.
5. A new prescription reads: "Amoxicillin 500 mg, i cap PO BID x 10 days." Which set of patient directions correctly translates this sig?
- A.Take one capsule by mouth once daily for 10 days
- B.Take two capsules by mouth once daily for 10 days
- C.Take one capsule by mouth twice daily for 10 days
- D.Take one capsule by mouth every other day for 10 days
Show answer and explanation
Correct answer: C. Take one capsule by mouth twice daily for 10 days
PO means by mouth and BID means twice daily, so the patient takes one capsule by mouth two times each day. The Roman numeral i indicates one capsule per dose, and the course length of 10 days comes directly from the sig.
6. Lipitor is the brand name for which generic medication?
- A.Rosuvastatin
- B.Simvastatin
- C.Atorvastatin
- D.Pravastatin
Show answer and explanation
Correct answer: C. Atorvastatin
Lipitor is the brand name for atorvastatin, an HMG-CoA reductase inhibitor (statin) used to lower cholesterol and reduce cardiovascular risk. Rosuvastatin (Crestor), simvastatin (Zocor), and pravastatin (Pravachol) are other statins in the same class but are marketed under different brand names.
7. A standard National Drug Code (NDC) is a 10-digit number divided into three segments. What do the three segments identify, in order from first to last?
- A.Product, labeler, package
- B.Package, product, labeler
- C.Labeler, product, package
- D.Labeler, package, product
Show answer and explanation
Correct answer: C. Labeler, product, package
The NDC reads labeler code first, product code second, and package code third. Reversing the last two segments is a common error: the product code sits in the middle and describes the drug itself, while the package code always comes last and describes the container.
8. Two pharmacies in the same chain electronically share a real-time, online database. How does this affect transfers of Schedule III-V prescription refill information between them under federal law?
- A.Transfers remain limited to one time only
- B.Transfers are prohibited between commonly owned pharmacies
- C.Each transfer requires a new hard-copy prescription
- D.They may transfer the prescription up to the maximum refills permitted by law and the prescriber's authorization
Show answer and explanation
Correct answer: D. They may transfer the prescription up to the maximum refills permitted by law and the prescriber's authorization
21 CFR 1306.25(a) creates an exception to the one-time transfer limit: pharmacies electronically sharing a real-time, online database may transfer a Schedule III-V prescription up to the maximum number of refills permitted by law and the prescriber's authorization. All documentation requirements for transfers still apply.
Ready for the full timed run? Scroll back up and start the Practice Test 1, or browse every free PTCB quiz by exam domain.
Key concepts to know
How to use the numbered series
Work through Test 1, then Test 2, and so on. Because the sets don't overlap, finishing several numbered tests exposes you to a wide spread of the bank without seeing the same question twice. Log the domain you miss most and drill it with the matching domain quiz.
Same weighting, smaller dose
The 20 questions keep the official proportions: 7 medications, 5 patient safety, 4 order entry, and 4 federal requirements, so your per-domain result is still a meaningful readiness signal.
Practice Test 1: FAQ
How is Practice Test 1 different from the 90-question exam?
It is a 20-question mini version for shorter sessions, weighted to the same four domains. Use the numbered mini tests for quick reps and the 90-question exam to build stamina for the real 110-minute sitting.
Will Test 1 and Test 2 show me the same questions?
No. Each numbered test draws from its own dedicated question set, so working through the series never repeats a question across tests.
Official sources checked
This quiz's content and explanations are built from and cross-checked against primary sources. Verify current exam facts directly with PTCB.
